inForce & inForce Platinum

Product Use Information

Coriolus versicolor has been used for centuries in Traditional Chinese Medicine. Known as Yun zhi in China and Kawaratake in Japan this mushroom was referenced in the Chinese Compendium of Materia Medica as far back as the 15th century.

The Ming dynasty edition of the Materia Medica states that " The black and green Yun zhi are beneficial to one's spirit and vital energy, and strengthen one's tendon and bone. If Yun zhi is taken for a long time, it will make one vigorous and live long."

Modern clinical research has focused on using the water extracts of this mushroom to stimulate and strengthen the immune health of people with cancer.

In Traditional East Asian Medicine the texts call for 6-12 gram of dried mushrooms per day, prepared in a tea. The daily amount, taken as tea, should be split between morning and evening.

The dried mushroom can easily be ground to a powder in a coffee grinder, or can be purchased already ground (please specify in order).

Bring the tea just to a boil then immediately turn down to a simmer. Do not boil the tea past the initial boil, it will degrade the medicinal compounds. For maximum benefit you can simmer the tea from 2-4 hours, although a fairly strong tea can be made in 20-30 minutes. The grounds can be re-heated with benefit, discard the grounds when they no longer produce color in the tea.

Filter the tea through a coffee filter before drinking. As mentioned the grounds can be re-used as long as they produce color in the tea. Any un-used portion of the tea can be refrigerated and used up to two days later. Shake the stored tea before using it.

While herbalists claim Coriolus versicolor and its extracts are useful against a number of conditions, including cancer and certain infections, it is unclear how effective extracts of the mushroom itself may be. These extracts are sold as dietary supplements in the United States.

Researchers have found that PSK, one of the substances that can be extracted from Coriolus versicolor, has several anti-cancer properties, including slowing the spread of cancer cells in the body. PSK also appears to have some immune boosting properties in people getting chemotherapy, and may lessen some side effects of chemotherapy and radiation therapy. PSK is also believed to be a strong antioxidant, a compound that blocks the action of activated oxygen molecules, known as free radicals, and can damage cells.

The effects of PSP are less well known. Some lab evidence suggests it may slow the growth of certain tumors, boost the immune system, and make radiation therapy work better, but it’s not clear whether it will have these effects in people.

What is the history behind Coriolus versicolor?

Coriolus versicolor has been a component of traditional Asian medicine for centuries. In the 1980s, the Japanese government approved the use of PSK for treating several types of cancers. In Japan, PSK is a best-selling anticancer drug. It is currently used as a cancer treatment in Japan along with surgery, chemotherapy, and radiation therapy. PSP was discovered more recently, and has been studied mainly in China.

What is the evidence?

We are unable to find reports of controlled clinical trials with the Coriolus versicolor mushroom itself in available peer-reviewed journals. However, there have been many studies looking at the usefulness of PSK. These studies have been done with PSK and not the mushroom.

More than 2 dozen human studies of PSK have been reviewed by experts at the University of Texas MD Anderson Cancer Center. Almost all of these studies were done in Japan and focused on cancers of the esophagus, stomach, colon, or breast. Most of them found that people with cancer were helped by PSK. People who received PSK along with other treatments, such as surgery, chemotherapy, or radiation therapy, generally had longer disease-free periods and increased survival rates compared with patients who got only standard treatment. Side effects from PSK in these studies were very mild. Smaller studies have suggested PSK may not be as effective against liver cancer or leukemia.

While some early Chinese studies of PSP have reportedly shown it may help protect the immune system from the effects of cancer treatment, most studies published in medical journals thus far have been in cell cultures or animals. Studies in animals have suggested that PSP may slow the growth of lung cancer and sarcoma, and may help make radiation more effective in treating certain brain tumors. One small study found that lung cancer patients taking PSP seemed to maintain their health longer than those who did not take PSP, although they did not get better and did not report improvement in cancer-related symptoms. Larger human studies will be needed to find out how effective PSP may be.

A 2005 study using mice treated with a chemical that causes colon cancer did not find any reduction in colon tumors in mice also given VPS, another extract of Coriolus versicolor. A 2006 study found that VPS may have actually increased the number of large colon tumors in mice.

Are there any possible problems or complications?

No serious risks have been linked with the use of Coriolus versicolor or PSK. Rarely, side effects include nausea, vomiting, loss of appetite, and diarrhea. Even less common are darkening of the fingernails and low blood cell counts.

Relying on this type of treatment alone, and avoiding or delaying conventional medical care, may have serious health consequences.

Patients with cancer frequently use herbs along with the conventional medical treatment, hoping to enhance recovery. Mushrooms have an established history of use in traditional oriental therapies. In Asian cultures, mushrooms are combined with herbal mixtures to treat cancer. This systematic review and meta-analysis draw from randomized, placebo-controlled, double-blind trials to assess the efficacy of Yun Zhi (YZ) for survival in cancer patients.

Name
Latin Name: Coriolus versicolor, synonym Trametes versicolor
Common Name: Turkey tail / Cloud mushroom
Scientific Name: Polystictus versicolor (L.) Fr.
Chinese Name: 雲芝 / 彩絨革蓋菌
Pinyin Name: yun zhi

Origin
The sporophore (fruiting body) or mycelium of Polystictus versicolor (L.) Fr., family Polyporaceae [1].

Where Does It Grow?
The wide giant fungal plant can be found on the spruces that located in 3000 meter attitude and distributed throughout most of China. Nowadays, the supply is mainly sourced from cultivation [1].

Nature and Flavor
Sweet and bland in flavors, slightly cold in nature, and mainly manifests its therapeutic actions in the spleen, lung and liver meridians [2].

Identified Active Components / Major Chemical Constituents
Cloud mushroom contains several saccharides including polysaccharide peptide (PSP) and polysaccharide-K (PSK, krestin). The protein bound polysaccharides have been found to be immune-modulating and anti-tumor, and their polypeptide moieties are rich in aspartic acid and glutamic acid. By gas chromatography and HPLC, PSP has proved that in addition to glucose, it also contains five other monosaccharides - mannose, xylose, galactose, rhamnose and arabinose. The polysaccharide peptides can be found in the mycelium, while the fruiting body mainly contains polysaccharides [3].

Drug actions in TCM
Replenish essence and qi (vital energy), general enhancement and regulate immune functions [1].

Traditional Uses in TCM
Invigorating spleen and eliminating dampness : for symptoms like general weakness, poor appetite and loose bowels. Modern used for hepatitis, hepatic cirrhosis, nephritis, and rheumatoid arthritis, etc. [2]

Polysaccharide peptide (PSP), isolated from COV-1 strain of Coriolus versicolor, is commonly used as an adjunct in cancer chemotherapy or health supplement in China.

Polysaccharopeptide (PSP) isolated from the edible mushroom Coriolus versicolor was tested for its potential as an anti-human immunodeficiency virus type 1 (HIV-1) compound in a series of in vitro assays.

Two major types of IBD are described: ulcerative colitis (UC) and Crohn's disease (CD). As the name suggests, ulcerative colitis is limited to the colon (large intestine). Although Crohn's disease can involve any part of the gastrointestinal tract from the mouth to the anus, it most commonly affects the small intestine and/or the colon.

I always knew that diabetes ran in my family, starting with my Dad (William T. Kaufman) who past away from type one diabetes. My brother Jerry was diagnosed with type 2 diabetes about 10 years a go and my other brother Bill was type one diagnoses. My twin sister Paulette is also type 2.

Early 2010 I had a job that required travel and I had recently returned from one of my long trips. I went to the cleaners to wash my close and while standing at the counter I blacked out and they thought I had a heart attack. When I came through I thought it was just jet lag and fatigue. I then went and got something to eat and drink and did not think of it as being diabetic.

Around mid July 2010 I was strolling on the beach with a friend when I got a splinter in the palm of my foot. I was very fatigue that day so I went home and took a three hour nap and when I woke I had a temp of 108 and my foot was swelling up and would not go down. Two or three days later I decided to go to the emergency because of the redness and swelling that had appeared. My temperature was still at 108 and my blood pressure was elevated. After they drew my blood they came back and said I had an infection that was so bad that they would have to admit me. At that time it had been about 4 hours since I ate so my sugar could have been around 600 plus should I have eaten however it was in the 300s. I was started on diabetic treatments with insulin shots immediately. I was very concern about my stay in the hospital because I was there for 9 days and my bill was over $30,000. It took them that long to stabilize my sugar levels. They finally found a splinter on the bottom of my foot and an ulcer between my toes about size of my pinky. This was an open ulcer with fluid draining from it. They sent me home on antibiotics, diabetic medication and blood pressure medications. I was told to clean my foot twice a day with iodine solution and to keep it elevated.

I went to an infectious disease Dr. for several weeks along with a foot specialist and primary Dr. No change was taken place in a positive direction however I had more fluid coming out and swelling that I have ever seen.

When I left the hospital I got a call form my friend Dan Gracia who briefly mentioned something about the inForce product based on the Coriolus Versicolor Mushroom. However I told Dan that I would do some research on it and I continued to do what the Dr. said by keeping my foot clean and staying off of it however it had gotten worst. Then about two weeks after the first call from Dan he called me again with his friend Jim Monde on the phone. At that time they where giving me a bunch of testimonies about this product.

The swelling and redness was getting so bad that it began to clime up my leg and it looked like I had Elephantitis and then other leg started to swell because I was depending on it so much. This entire time I had walked with a walker.

I was scheduled for a Dr.’s appointment the same week that Dan, Jim and I talked and I was not feeling good on the inside about what the Dr. might say because by this time I had been out of work for a couple of months and things where not looking good. I started thinking about my two brothers that are ready to loose there life. Both with cancer and the one with sever infections from a bad surgery. I went to the Dr. and as my gut was telling me he gave me the bad news that we would have to amputate my foot due to the infections. That was on the Thursday prior to the memorial weekend. After leaving the Dr.’s office I remembered what Dan and Jim had told me and started to pray about it. I then called Dan and gave him the bad news. Dan then told me that he would make a rush 24 hour order so that I would not have to spend the holiday weekend without the inForce product. The product arrived on the next day Friday and I immediately started to take them. I averaged about 7 pills a day until I saw the Dr. on Tuesday after the holiday. The Dr. stated to me that we are seeing a turn around here and healing of about 20-30% and it had only been 5 days since I started the product. After 7 days I saw more improvement and decided to increase my intake to 12 capsules a day. The following week I went back to the Dr. and he could not believe the rate of healing. He said it was improving so rapidly that the ulcer was healing up, the swelling was going down, the redness was subsiding and the fluid was slowing down. He also mentioned that at this pace I could be off of my crouches within a week to two weeks. I am scheduled to see him on September 26, 2010 I currently am still taking the product and have seen great improvement and also have notice my sugars’ are not bottoming out and blood pressure is staying normal. Because of the diabetes I have cataracts and bleeding behind the eyes. I have noticed improvement in my vision and I can’t wait to see what my eye Dr. has to say when I see him on November 12th to determine my surgery options for my eyes.

I am feeling much more energy, my skin is tightening and much smoother. I had a split finger nail from a fungus and it would not heal for over a year, it is now almost all healed. I don’t wake up in the middle of the night from sugar lows any more and my ringing in the ears has stopped. My mind is feeling sharper and I don’t feel like I have any forgetfulness.

This is a product that I recommend for anyone and everyone because the medical community is not telling us the entire truth about earths natural benefits. I want to thank the almighty, Dan Gracia, Jim Monde and inLife for introducing me to an amazing miracle product that I know will change the world.

Yours Truly

Love and blessings

Paulyah Ezekiel Kaufman